Unix-C Lotion

✔️ Uses of Unix-C Lotion

• Scabies (skin infection)
• Pruritic (itchy skin)

✔️ How does Unix-C Lotion work?

Permethrin is an antiparasitic medication that effectively kills tiny insects (mites) and their eggs, responsible for causing scabies. It is also effective against head lice that attach to the scalp and cause irritation.

Crotamiton belongs to two classes of medicines, antipruritics, and scabicides. As an antipruritic, it helps relieve itching. Simultaneously, as a scabicide, it works to kill the mites that cause scabies, providing relief from the condition.

✔️ Side Effects of Unix-C Lotion

• Skin irritation
• Skin redness
• Burning or tingling sensation at the site of application
• Trouble breathing

✔️ Quick Suggestions:

• Permethrin+ Crotamiton is prescribed for the treatment of scabies( a condition where tiny insects infest and irritate your skin).
• It should be used as per the dose and duration suggested by your doctor.
• Avoid getting it in your eyes, nose, or mouth. If this happens, rinse with water immediately.
• Apply a thin layer of medicine all over the body and leave it for 24-48 hours before taking a bath or shower.
• Wash your hands before and after applying the medicine.
• If the condition persists after 14 days of treatment then the doctor may suggest another treatment.

✔️ Indication of Unix-C Lotion

A scabicide and antipruritic drug is Unix C. It is used to treat scabies, skin irritation, and infestation caused by microscopic insects. It kills the mites and their eggs in order to function. It is also used to treat skin irritation and itching.

✔️ Pharmacology

Permethrin is a pyrethroid bactericide and a scabicide. It causes paralysis and death of parasites by inhibiting the influx of sodium ions through neuronal membrane channels slowing repolarization.

Crotamiton has bactericidal and antipruritic effects against Sarcoptes scabei. It is also an effective germicide.

✔️ Dosage & Administration of Unix-C Lotion

Unix-C Lotion is suitable for adults, children aged 2 months and above, and the elderly. It should only be used externally and should not be applied to broken skin, mucous membranes, or near the eyes.

To use Permethrin & Crotamiton lotion:

1. Apply the lotion to clean, dry, and cool skin. Avoid using it immediately after a hot bath.
2. Apply the lotion to the entire body, excluding the head. Pay special attention to areas between fingers and toes, under nails, wrists, armpits, external genitalia, breasts, and buttocks.
3. For adults and children over 2 years old, apply the lotion to the whole body, except the head and face. For the elderly, apply the lotion to the entire body, including the neck, face, ears, and scalp.
4. Children under 2 years should only be treated under medical supervision. Apply the lotion to the whole body, including the neck, face, ears, and scalp. Avoid the mouth area, where the lotion could be ingested, and the eye area.
5. Leave the lotion on for at least 8 hours. If hands are washed within 8 hours of treatment, reapply the lotion to them.
6. Wash the entire body thoroughly 8-12 hours after application.
7. Clean clothes and bed sheets with warm water the next day. Reapply the lotion if it gets washed out.
8. Other family members should use the lotion preventively in the same manner, as scabies is highly contagious.
9. Avoid applying the lotion near the mouth and the areas around the eyes.

✔️ Interaction

Before starting treatment with permethrin for scabies, corticosteroids should be discontinued to avoid treating eczema-like reactions. Using corticosteroids can reduce the immune response to mites, potentially exacerbating the scabies infection. However, the interaction between permethrin and corticosteroids is unlikely to increase adverse effects or reduce the effectiveness of the scabies treatment. It is essential to follow the prescribed treatment plan and consult with a healthcare professional to ensure the most effective and safe management of scabies.

✔️ Contraindications

The combination of permethrin 5% and crotamiton 10% is contraindicated in patients known to be sensitive to permethrin or crotamiton.

✔️ Pregnancy & Lactation

There is no experience to assess the safety of permethrin and crotamiton during pregnancy and therefore should not be used during pregnancy, especially during the first trimester. It is not known whether the active substance passes into breast milk. Breastfeeding mothers should avoid applying to the nipple area.

✔️ Precautions & Warnings

• Keep the lotion out of the reach of children to prevent accidental ingestion.
• This lotion is meant for external use only, and it should not be ingested.
• Caregivers who frequently apply the lotion should consider wearing gloves to avoid any potential skin irritation.
• Avoid getting the lotion into the eyes, as it can cause irritation. If accidental eye contact occurs, rinse the eyes immediately with water.

✔️ Storage Conditions

Store in a cool place (do not store above 25° C & do not freeze) and protected from light.